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Trachoma: Protective and Pathogenic Ocular Immune Responses to Chlamydia trachomatis

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According to the paper, an increasing number of studies that have been conducted over the span of time indicate towards the fact that innate immune responses that arise from the epithelium and some other innate immune cells, as well as the changes that occur in matrix metalloproteinase activity, are extremely important and crucial for the increase in tissue damage and scarring caused by Chlamydia trachomatis (Ct). The current and recent measures for the control of are all majorly centered on the repetitive and constant antibiotic treatment of mass populations are extremely challenging from the logistical point of view and also have the potential to drive antimicrobial resistance.

A vaccine for trachoma would offer significantly large advantages and will be probably extremely beneficial. However, the limited understanding of the mechanisms and procedures involving both the protective immunity and immunopathology for Chlamydia trachomatis (Ct) remain huge hindrances to the process of vaccine development. Vaccine development seems to be the logical option to curb this menace but it still needs to be seen if effective vaccination can be developed keeping in all the progressions that involve curing by Chlamydia trachomatis (Ct). The media article ‘ Curable eye disease still rife among Indigenous Australians’ published on 15th of March, 2013, it is clearly stated that Australia is perhaps the only country in the developed category that has still not been able to effectively deal with the problem of trachoma despite knowing the fact how potentially dangerous this disease is and what it can lead to eventual blindness.

The article talks about how this disease is still prevalent in the indigenous communities in Australia.

article talks about how the numbers of this disease have decreased in the last 4 years during the tenure of the current government but how more work is required to deal with the problem. Basically it’ s a matter of funds and their inadequacy that form the major barrier to dealing with this problem.  

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