So when an individual has reduced, or the dose reduce in the blood also the happiness causing hormone, dopamine, also goes down and the craving also start to go back to normal. The drugs taken tend to increase dopamine and when withdrawn the level of this dopamine dwindle and the cycle repeat itself. This cycle is what is known as drug addiction (Hanson, 2005).Will power to withdraw from drugs is most a time futile. The physiologic development of regulation effect dopamine with administrative drugs is the causative factor. The individual with drug addiction may have the will to withdraw from the use of the drug, but the will cannot have an effect on levels of dopamine hence the craving of the drug continue. In addition, the receptor cells that dopamine act on them have developed tolerance level of a certain level of dopamine. Any lower levels will cause sadness, states of depression and headache migraine. The will to withdraw from the drugs cannot reverse the tolerance levels of this receptor cells to dopamine. Therefore, indulgence into drug use is by individual will but the withdrawal from addiction is not the will power since is strongly a physiological process that alter the somatic physiological operating systems.Factors involved in someone undergoing addiction of drugs mainly are in the brain. However, they start with the individual effort physically. The first factor is the small use of the drugs that the body sustains with time. With continuous use, the body starts tolerating the small dose of the substance or prescribed drug that is being used. This lead to increase in the dose of the drug as the body has tolerated the initial small dose. With this increase, factors involved are mainly attached to the brain. The dopamine neuron activated by GABA hormone and opioids start undergoing modulation. GABA has an inhibitory effect on the activity of dopamine, which mainly is to cause happiness while the opioids taken as the substances have an effect of inhibiting GABA and activating the neuron cell to cause happiness. Most of the substances taken are known to activate opioid receptors such u and k-receptors. These consequently lead to accumulation of dopamine hormone. The activation is due to inhibition of the GABA.This includes beer, wine and in other liquor. In low doses, alcohol causes euphoria and mild stimulation and relaxation effect. The side effects
Ausubel, D. P. (2008). Drug addiction: physiological, psychological, and sociological aspects. New York, Random House.
DE Grazia, J. (2011). DEA: the war against drugs. London, BBC Books.
Hanson, G., Venturelli, P. J., & Fleckenstein, A. E. (2005). Drugs and society. http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&A N=667376.
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