So when an individual has reduced, o the dose reduce in the blood also the happiness causing hormone, dpamine, aso goes down and the craving also start to go back to normal. Te drugs taken tend to increase dopamine and when withdrawn the level of this dopamine dwindle and the cycle repeat itself. Tis cycle is what is known as drug addiction (Hanson, 2005). Wll power to withdraw from drugs is most a time futile. Te physiologic development of regulation effect dopamine with administrative drugs is the causative individual with drug addiction may have the will to withdraw from the use of the drug, bt the will cannot have an effect on levels of dopamine hence the craving of the drug continue.
I addition, te receptor cells that dopamine act on them have developed tolerance level of a certain level of dopamine. Ay lower levels will cause sadness, sates of depression and headache migraine. Te will to withdraw from the drugs cannot reverse the tolerance levels of this receptor cells to dopamine. Terefore, idulgence into drug use individual will but the withdrawal from addiction is not the will power since is strongly a physiological process that alter the somatic physiological operating systems.
Fctors involved in someone undergoing addiction of drugs mainly are in the brain. Hwever, tey start with the individual effort physically. Te first factor is the small use of the drugs that the body sustains with time. Wth continuous use, te body starts tolerating the small dose of the substance or prescribed drug that is being used. Tis lead to increase in the of drug as the body has tolerated the initial small dose.
Wth this increase, fctors involved are mainly attached to the brain. Te dopamine neuron activated by GABA hormone and opioids start undergoing modulation. GBA has an inhibitory effect on the activity of dopamine, wich mainly is to cause happiness while the opioids taken as the substances have an effect of inhibiting GABA and activating the neuron cell to cause happiness. Mst of the substances taken are known to activate opioid receptors such u and k-receptors. Tese consequently to accumulation dopamine hormone.
Te activation is due to inhibition of the GABA. Tis includes beer, wne and in other liquor. I low doses, acohol causes euphoria and mild stimulation and relaxation effect. Te side effects. ..
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