For instance, te polyesters produced by the microorganisms will be used in medical applications like sutures, iplants, ad urological stents. I addition to this, te polyesters will be used in the treatment of narcolepsy as well as alcohol addiction. Bologic products are derived from natural (biological) products. Tey include medical products such as vaccines, bood products, ad allergenic extracts such as allergy shots. Anatural product, o the other hand, i a product of a living organism. Ntural products were the main components of traditional medicines. Crrently, tey are in many modern medicines.
Hstorically, bologic products have been more significant for applied microbiology (Li & Vederas, 2009). Tis is evidenced by the generation of the majority of new drugs from natural products. Te identification, rsing, ad marketability of drugs from natural products has been affected by many factors. Fr instance, te most current difficulties are associated with technical limitations in determining new compounds for the drugs and the existing standard for drug identification in big pharmaceutical industries (Li & Vederas, 2009). Te increase in expectations by the shareholders result of the double-digit yearly sales has also posed a great challenge to the production of drugs from natural resources.
I addition to this, te loss of patent protection hampers with the marketability of the drug. Fr instance, te US was predicted to lose $63 billion in its annual income for pharmaceutical industries because of approximately 25% of the US drug market losing patent protection (Li & Vederas, 2009). Poduction of drugs from biologic products is also associated with some challenges. Fr instance, crrently it is very difficult discover source of the natural product drug (Li & Vederas, 2009).
Acessibility and supply of natural sources also pose a great challenge to the production of biologic products. Te usability of drugs with complex structure as a result of being generated from higher plants also present a big challenge. A example of a drug with complex structure is paclitaxel, a anti-tumor agent taxol (Li & Vederas, 2009). Plyhydroxy-Alcanoates (PHA) and Polyhydroxy-Butyrate (PHB) are a form of biodegradable plastics that are synthesized by microorganisms (Garcia et al. Tese polyesters used as source of carbon as well as energy.
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