SSRIs (selective serotonin re uptake inhibitors), NRIs (norepinephrine re uptake inhibitors, e., atomoxetine, etc. ) SNRIs (selective serotonin-norepinephrine re uptake inhibitors), Tricyclics and related compounds, CYP2D6 (liver enzyme) inhibitors, including methadone. Evidence exists that Adderal can significantly reduce symptoms of ADHD, and depending on the dosage, symptoms can be alleviated sufficiently for improvement throughout the work/school day. Low doses of Adderal appear to have long periods of efficacy, according to some studies for a longer duration than Ritalin/Methylphenidate. (Health and Life, Adderal 2011)In the long term, effects include increased focus and motivation (reduction of ADHD symptoms) The areas of the brain that control these areas have been shown to actually increase in size.
But a Free-Radical buildup in the brain may necessitate the use of anti-oxidants. The drug may also be described as diet pills due to an appetite-suppressant function, which can lead to weight-loss. The drug has been shown to maintain efficacy for several years even with a consistent dose every day. In the majority of patients, the potency does not appreciably diminish. (Health and Life, Adderal 2011)Side effects can include increased blood pressure, with the accompanying risk of stroke, sudden death, and heart attack, but so does Methylphenidate/Ritalin In addition, it can exacerbate risk factors in patients with a history of seizures.
(Adderal XR, 2009)Adderall appears stronger than Ritalin on a per-molecule basis, which allows the patient to take less of it. Numerous studies show that Adderall is slightly more effective at controlling ADHD symptoms, however in many studies, these differences were so marginal that they were not statistically significant, however - these marginal benefits occurred across many different studies; enough that the number of slightly beneficial outcomes convinces some researchers that the differences are significant.
Staff Clinicians at SUNY Buffalo were found to prefer it 3 to 1 over Ritalin/Methylphenidate. (Health and Life, Adderal 2011)the prodrug, an inactive delivery agent that converts to an active form when it metabolizes inside the body later on. This measure is intended to limit the potential for abuse; the pill will only convert to the active form of the drug through oral ingestion into the gastrointestinal tract.
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