Garlic had shown many positive signs of lowering the cholesterol level in hypercholesterolemia cases in many studies. In a study conducted by Mahmoodi M, Islami MR, Asadi Karam GR, Khaksari M, Sahebghadam Lotfi A, Hajizadeh MR, Mirzaee MR 2006, showed a decrease in serum lipids but garlic cannot be used solely as a therapeutic agent. But Gardner CD, Lawson LD, Block E, Chatterjee LM, Kiazand A, Balise RR, Kraemer HC. 2007 did a study to investigate the effect of raw and processed garlic on such high cholesterol cases and found out no significant effect on the LCD or plasma lipid profile.
Trikatu, a combination of Piper longum, Piper nigrum (fruit) and Zingiber officinale (rhizome) dry powder, was found to be of great benefit as a hypolipidemic agent confirms a study done by Sivakumar V, Sivakumar S. 2004. Any toxic or side effects identified through previous clinical trials? Of Garlic or trikatu? Allergic reactions such as colitis have been reported on the use of garlic. Also, the prolonged application of garlic on the skin especially its extract Allicin may cause skin burns.
Some people even experience gastrointestinal discomfort. High concentrations of garlic have illustrated toxic and fatal effects on animals. More research needs to be conducted on this issue. Studies have shown the benefits of garlic on lipid profile by decreasing LDL levels and raising HDL levels. Aged garlic has shown better results. Trikatu is an ayurvedic compound known to increase absorption and bioavailability of drugs and is often prescribed with other formulations by ayurvedic doctors. Asian men are pre-disposed to raised cholesterol levels and cardiovascular disease, especially migrant British Asian men.
The importance of diet and lifestyle on reducing raised cholesterol risk factors for cardiovascular disease. The success rate of modified diet and exercise programmes on reducing and maintaining raised cholesterol levels. If food supplements like garlic and Trikatu can further help reduce raised cholesterol and prevent the intake of statin and other cholesterol-reducing drugs Garlic is known to reduce moderately raised cholesterol.
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